San Francisco 49ers at Kansas City Chiefs — Week 16 Odds, Injuries & Prediction

San Francisco 49ers @ Kansas City Chiefs: live odds, injury report, team rankings comparison, and win probability for this matchup.

Sun, Dec 27 · 4:25 PM ET · CBS

Odds (DraftKings): KC -3 · ML SF +130 / KC -155 · O/U 46.5

Model prediction

Predicted winner: Kansas City Chiefs - SF 20% / KC 80%

Team stats comparison (rank out of 32)

	SF offense	KC offense	Edge
Total yards	#7	#20	away edge (13)
Rush yards	#24	#25	away edge (1)
Pass yards	#5	#16	away edge (11)

	SF defense	KC defense	Edge
Total yards allowed	#20	#10	home edge (10)
Rush yards allowed	#11	#9	home edge (2)
Pass yards allowed	#25	#12	home edge (13)

Injury report

• Mike Evans (SF · WR) - questionable - Quad strain
• George Kittle (SF · TE) - out - Torn Achilles tendon
• Ricky Pearsall (SF · WR) - out - PCL knee surgery - season-ending
• Nick Bosa (SF · Edge) - out - Knee tendinitis (surgically repaired right knee)

San Francisco 49ers full schedule · Kansas City Chiefs full schedule · See this week's full NFL odds and predictions on Blitz Odds